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Combinatorial chemistry has been an estabished technology for fast access to large number of compounds for screening. It is reported that over 50% of the new drug leads originated from combinatorial chemistry in recent years. It has also become a routine technique in lead optimization and process development. CDS devotes to design and synthesis of novel drug-like scaffolds and focused libraries, and has developed technologies to access pyrimidine fused analogs (such as purine analogs and pteridine analogs), indole analogs, -lactam analogs, benzene fused analogs, pyridine fused analogs, and diazepine analogs. With the high throughput chemistry platform and experience in organic synthesis, CDS provides short path to novel drug-like molecules. (In the graph below, syntheses of pyrimidine fused scaffolds are shown as an example.)

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